How do we feel about questions about biological principles that can be confusing to a bioinformatician with no background in biology? While purely biological questions should, I think, be off topic and migrated to Biology, what about questions from bioinformaticians trying to interpret their results?
For example, if someone were to ask about what these weird
0/1 things they see in a VCF file, should we explain what haplotypes and zygosity are? If someone asks about how a PPI network is generated, should we explain ChIP or Y2H methods here?
Basically, how strict is our definition of bioinformatics? This is a subfield of biology, after all.